No, I don't think this can happen. If a person is open to every influence and person they come across, practice and aren't afraid to fail, multiple times, decades on end, if they're honest about what it is exactly that they're trying to accomplish and strive towards it with a sense of humor and dedication, given enough time, I think this person will attain their goal.
The question is whether most people are willing to do all this. If you're willing to fail at the thing you love the most for the next fifty years, and that entire time get no encouragement or proof that you're ever going to get any better, in the hopes that after all that time has passed you will one day succeed, this is a true artist.
I just keep my fingers crossed that I'll still feel this way in fifty years!!